Risk Stratification in Arrhythmic Mitral Valve Prolapse (Mitral Annular Dysjunction)

 

Myocarditis Management - Circulation:Heart Failure (Adult)

 

Coronary Fistula vs. VSD. Difference in Doppler trace (timing of the trace)

Doppler flow peak in systole in VSD, but it peaks in diastole in coronary fistula.
 

Bronchopulmonary dysplasia_Pulmonary Hypertension_European algorithm

 From Hansmann G, et al. Pediatr Research 2021;89:446-455.

Rivaroxaban (Xarelto) for Post-Fontan children

Source: Manufacturer webpage

UNIVERSE clinical trial

• n = 112 (Final n = 98, 64 Rivaroxaban, 34 Aspirin)
• Randomized 2:1 (Rivaroxaban : Aspirin) 
• Open label Rivaroxaban vs. Usual Aspirin.
• Age 2-8 yrs
• Follow up for 12 months.

 

Myocarditis risk is lower if interval between doses of Covid Vaccine increased to > 8 weeks (CDC slide)

 

Causes of Troponin elevation

 

Circulation 2011;124:2350-4.

Kobayashi Score 2006 - Kawasaki disease

 

Normal values_BP_2017_AAP

 Reference: https://doi.org/10.1542/peds.2017-1904

Girls

Boys:

https://link.springer.com/article/10.1007/s11906-017-0780-8/tables/3 

Anti-viral therapy for Covid (as of 1/5/22)

 1) Sotrovimab IV (GSK) - Monoclonal antibodies - reduces hospitalization by 90%, effective against Omicron variant.

2) Oral Paxlovid (Nirmatlevir/Ritonavir, Pfizer)  - x 5 days - reduces hospitalization by 90%.

3) Remdesvir IV (Gilead) - x 3 days - reduces hospitalization by 90%.

4) Oral Molnupiravir (Merck) - x 5 days - reduces hospitalization by 30%.