Lamour, JM, et al. (from Columbia, NY)
J Heart Lung Transplant 2004;23:948-5311 patients with single lung physiology from congenital heart disease.
TOF with absent LPA - 4,
Single Ventricle s/p Classic Glenn - 7 (Absent LPA 1, Severe LPA hypertension 6)
Cause of LPA hypertension in the 6 pts:
Pulmonary vein stenosis 3, Waterston shunt 1 and AP collateral 2.
Preop. mean RPA pressure:
TOF patients - 29 ± 10 mmHg
Classic Glenn patients - 15 ± 4 mmHg
PA angiograms showed normal branch pattern of RPA.
Lung perfusion scan showed 80% flow to right lung in patients with LPA hypertension.
Age range at Heart Transplant: 9 - 43 yrs.
Outcome:
Early postop death 2 (Aortic rupture 1, Bleeding 1) - 82% operative survival.
Late death 1 (Rejection at 3 yrs)
8/11 are alive at 4 yrs.
LPA continuity was established in 6 pts: Post-op lung perfusion scan did not show increase in flow to LPA.
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